{"id":8014,"date":"2023-07-17T15:23:59","date_gmt":"2023-07-17T07:23:59","guid":{"rendered":"https:\/\/www.huashu-tech.com\/?p=8014"},"modified":"2024-02-27T19:30:43","modified_gmt":"2024-02-27T11:30:43","slug":"designed-protein-switch-allows-unprecedented-control-over-living-cells","status":"publish","type":"post","link":"https:\/\/www.huashu-tech.com\/vi\/designed-protein-switch-allows-unprecedented-control-over-living-cells\/","title":{"rendered":"C\u00f4ng t\u1eafc protein \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf cho ph\u00e9p ki\u1ec3m so\u00e1t ch\u01b0a t\u1eebng c\u00f3 \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ebf b\u00e0o s\u1ed1ng"},"content":{"rendered":"<p>C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 t\u1ea1o ra c\u00f4ng t\u1eafc protein ho\u00e0n to\u00e0n nh\u00e2n t\u1ea1o \u0111\u1ea7u ti\u00ean c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng b\u00ean trong t\u1ebf b\u00e0o s\u1ed1ng \u0111\u1ec3 s\u1eeda \u0111\u1ed5i \u2014 ho\u1eb7c th\u1eadm ch\u00ed ch\u1ec9 huy \u2014 m\u1ea1ch b\u00ean trong ph\u1ee9c t\u1ea1p c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n<section class=\"article-banner first-banner ads-336x280\">\n<div id=\"div-gpt-ad-1449240174198-2\"><\/div>\n<\/section>\n<p>&nbsp;<\/p>\n<p>C\u00f4ng t\u1eafc n\u00e0y c\u00f3 t\u00ean l\u00e0 LOCKR, vi\u1ebft t\u1eaft c\u1ee7a Latching, Orthogonal Cage\/Key pRotein.<\/p>\n<p>C\u00e1c b\u00e0i b\u00e1o \u0111i k\u00e8m \u0111\u0103ng ng\u00e0y 24\/7 tr\u00ean t\u1ea1p ch\u00ed\u00a0<i>Thi\u00ean nhi\u00ean<\/i>\u00a0m\u00f4 t\u1ea3 thi\u1ebft k\u1ebf c\u1ee7a LOCKR v\u00e0 tr\u00ecnh di\u1ec5n m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng th\u1ef1c t\u1ebf c\u1ee7a c\u00f4ng ngh\u1ec7. C\u00f4ng vi\u1ec7c \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi c\u00e1c nh\u00f3m k\u1ef9 thu\u1eadt sinh h\u1ecdc do David Baker t\u1ea1i Vi\u1ec7n Thi\u1ebft k\u1ebf Protein UW v\u00e0 Hana El-Samad t\u1ea1i UC San Francisco d\u1eabn \u0111\u1ea7u.<\/p>\n<p>C\u00e1c nh\u00e0 khoa h\u1ecdc cho th\u1ea5y LOCKR c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u201cl\u1eadp tr\u00ecnh\u201d \u0111\u1ec3 s\u1eeda \u0111\u1ed5i\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/gene+expression\/\" rel=\"tag\">bi\u1ec3u hi\u1ec7n gen<\/a>, chuy\u1ec3n h\u01b0\u1edbng l\u01b0u l\u01b0\u1ee3ng t\u1ebf b\u00e0o, l\u00e0m suy gi\u1ea3m c\u00e1c protein c\u1ee5 th\u1ec3 v\u00e0 ki\u1ec3m so\u00e1t\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/protein\/\" rel=\"tag\">ch\u1ea5t \u0111\u1ea1m<\/a>\u00a0t\u01b0\u01a1ng t\u00e1c r\u00e0ng bu\u1ed9c. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u c\u0169ng s\u1eed d\u1ee5ng LOCKR \u0111\u1ec3 x\u00e2y d\u1ef1ng c\u00e1c m\u1ea1ch sinh h\u1ecdc m\u1edbi ho\u1ea1t \u0111\u1ed9ng gi\u1ed1ng nh\u01b0 c\u00e1c c\u1ea3m bi\u1ebfn t\u1ef1 \u0111\u1ed9ng. C\u00e1c m\u1ea1ch n\u00e0y ph\u00e1t hi\u1ec7n c\u00e1c t\u00edn hi\u1ec7u t\u1eeb m\u00f4i tr\u01b0\u1eddng b\u00ean trong ho\u1eb7c b\u00ean ngo\u00e0i t\u1ebf b\u00e0o v\u00e0 ph\u1ea3n h\u1ed3i b\u1eb1ng c\u00e1ch th\u1ef1c hi\u1ec7n c\u00e1c thay \u0111\u1ed5i \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o. \u0110i\u1ec1u n\u00e0y gi\u1ed1ng nh\u01b0 c\u00e1ch m\u1ed9t b\u1ed9 \u0111i\u1ec1u nhi\u1ec7t c\u1ea3m nh\u1eadn\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/ambient+temperature\/\" rel=\"tag\">nhi\u1ec7t \u0111\u1ed9 m\u00f4i tr\u01b0\u1eddng xung quanh<\/a>\u00a0v\u00e0 ch\u1ec9 \u0111\u1ea1o h\u1ec7 th\u1ed1ng s\u01b0\u1edfi ho\u1eb7c l\u00e0m m\u00e1t t\u1ef1 t\u1eaft ngay khi \u0111\u1ea1t \u0111\u1ebfn nhi\u1ec7t \u0111\u1ed9 mong mu\u1ed1n.<\/p>\n<p>Sau khi \u0111\u01b0\u1ee3c l\u1eafp r\u00e1p b\u1edfi m\u1ed9t t\u1ebf b\u00e0o, c\u00e1c c\u00f4ng t\u1eafc m\u1edbi n\u00e0y ch\u1ec9 c\u00f3 k\u00edch th\u01b0\u1edbc 8 nanomet \u1edf c\u1ea1nh d\u00e0i nh\u1ea5t c\u1ee7a ch\u00fang. C\u1ea7n h\u01a1n m\u1ed9t tr\u0103m tri\u1ec7u \u0111\u1ec3 trang tr\u1ea3i kho\u1ea3ng th\u1eddi gian \u1edf cu\u1ed1i c\u00e2u n\u00e0y.<\/p>\n<p>El-Samad, Gi\u00e1o s\u01b0 H\u00f3a sinh v\u00e0 L\u00fd sinh c\u1ee7a Gia \u0111\u00ecnh Kuo t\u1ea1i UCSF v\u00e0 \u0111\u1ed3ng t\u00e1c gi\u1ea3 c\u1ea5p cao c\u1ee7a b\u00e1o c\u00e1o cho bi\u1ebft: \u201cKh\u1ea3 n\u0103ng ki\u1ec3m so\u00e1t t\u1ebf b\u00e0o b\u1eb1ng c\u00e1c protein thi\u1ebft k\u1ebf m\u1edf ra m\u1ed9t k\u1ef7 nguy\u00ean m\u1edbi c\u1ee7a sinh h\u1ecdc\u201d. \u201cC\u0169ng theo c\u00e1ch \u0111\u00f3\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/integrated+circuits\/\" rel=\"tag\">m\u1ea1ch t\u00edch h\u1ee3p<\/a>\u00a0\u0111\u00e3 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho s\u1ef1 b\u00f9ng n\u1ed5 c\u1ee7a ng\u00e0nh c\u00f4ng nghi\u1ec7p chip m\u00e1y t\u00ednh, nh\u1eefng c\u00f4ng t\u1eafc sinh h\u1ecdc linh ho\u1ea1t v\u00e0 n\u0103ng \u0111\u1ed9ng n\u00e0y c\u00f3 th\u1ec3 s\u1edbm m\u1edf kh\u00f3a kh\u1ea3 n\u0103ng ki\u1ec3m so\u00e1t ch\u00ednh x\u00e1c \u0111\u1ed1i v\u1edbi ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o s\u1ed1ng v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 s\u1ee9c kh\u1ecfe c\u1ee7a ch\u00fang ta.\u201d<\/p>\n<figure class=\"mb-4\">\n<div class=\"plyr plyr--full-ui plyr--video plyr--html5 plyr--fullscreen-enabled plyr--paused plyr--stopped plyr--pip-supported plyr__poster-enabled\" tabindex=\"0\">\n<div class=\"plyr__controls\">\n<p><button class=\"plyr__controls__item plyr__control\" type=\"button\" data-plyr=\"play\" aria-label=\"Ch\u01a1i\"><span class=\"label--not-pressed plyr__sr-only\">Ch\u01a1i<\/span><\/button><\/p>\n<div class=\"plyr__controls__item plyr__progress__container\">\n<div class=\"plyr__progress\"><input id=\"plyr-seek-3294\" role=\"slider\" autocomplete=\"off\" max=\"100\" min=\"0\" step=\"0.01\" type=\"range\" value=\"0\" data-plyr=\"seek\" aria-label=\"T\u00ecm ki\u1ebfm\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"0\" aria-valuetext=\"00:00 of 00:00\" \/><progress class=\"plyr__progress__buffer\" role=\"progressbar\" value=\"0\" max=\"100\" aria-hidden=\"true\"><\/progress><span class=\"plyr__tooltip\">00:00<\/span><\/div>\n<\/div>\n<div class=\"plyr__controls__item plyr__time--current plyr__time\" aria-label=\"Th\u1eddi \u0111i\u1ec3m hi\u1ec7n t\u1ea1i\">00:00<\/div>\n<div class=\"plyr__controls__item plyr__volume\"><button class=\"plyr__control\" type=\"button\" data-plyr=\"mute\"><span class=\"label--not-pressed plyr__sr-only\">T\u1eaft ti\u1ebfng<\/span><\/button><input id=\"plyr-volume-3294\" role=\"slider\" autocomplete=\"off\" max=\"1\" min=\"0\" step=\"0.05\" type=\"range\" value=\"1\" data-plyr=\"volume\" aria-label=\"\u00c2m l\u01b0\u1ee3ng\" aria-valuemin=\"0\" aria-valuemax=\"100\" aria-valuenow=\"100\" aria-valuetext=\"100.0%\" \/><\/div>\n<div class=\"plyr__controls__item plyr__menu\"><button class=\"plyr__control\" type=\"button\" aria-haspopup=\"true\" aria-controls=\"plyr-settings-3294\" aria-expanded=\"false\" data-plyr=\"settings\"><span class=\"plyr__sr-only\">C\u00e0i \u0111\u1eb7t<\/span><\/button><\/div>\n<p><button class=\"plyr__controls__item plyr__control\" type=\"button\" data-plyr=\"pip\"><span class=\"plyr__sr-only\">PIP<\/span><\/button><button class=\"plyr__controls__item plyr__control\" type=\"button\" data-plyr=\"fullscreen\"><span class=\"label--not-pressed plyr__sr-only\">V\u00e0o to\u00e0n m\u00e0n h\u00ecnh<\/span><\/button><\/p>\n<\/div>\n<div class=\"plyr__video-wrapper\">\n<p><video id=\"jwVID57461\" class=\"embed-responsive embed-responsive-16by9\" poster=\"https:\/\/scx1.b-cdn.net\/gfx\/video_tmb\/2019\/designedprot.mp4.jpg\" width=\"300\" height=\"150\" data-poster=\"https:\/\/scx1.b-cdn.net\/gfx\/video_tmb\/2019\/designedprot.mp4.jpg\" data-mce-fragment=\"1\"><\/video><\/p>\n<div class=\"plyr__poster\"><\/div>\n<\/div>\n<p><button class=\"plyr__control plyr__control--overlaid\" type=\"button\" data-plyr=\"play\" aria-label=\"Ch\u01a1i\"><span class=\"plyr__sr-only\">Ch\u01a1i<\/span><\/button><\/p>\n<\/div><figcaption class=\"text-darken text-low-up mt-4\">C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i Vi\u1ec7n Thi\u1ebft k\u1ebf Protein c\u1ee7a UW \u1edf Seattle gi\u1ea3i th\u00edch c\u00e1ch h\u1ecd v\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc California San Francisco t\u1ea1o ra m\u1ed9t c\u00f4ng t\u1eafc protein t\u1ed5ng h\u1ee3p, LOCKR, t\u1eeb \u0111\u1ea7u. Cu\u1ed9c th\u1ea3o lu\u1eadn v\u1ec1 m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng m\u00e0 h\u1ecd t\u00ecm th\u1ea5y \u0111\u1ed1i v\u1edbi c\u00e1c phi\u00ean b\u1ea3n LOCKR trong vi\u1ec7c ki\u1ec3m so\u00e1t m\u1ed9t s\u1ed1 qu\u00e1 tr\u00ecnh trong t\u1ebf b\u00e0o s\u1ed1ng. T\u00edn d\u1ee5ng: Y h\u1ecdc UW<\/figcaption><\/figure>\n<p>Kh\u00f4ng c\u00f3 \u0111\u1ed1i t\u00e1c trong\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/natural+world\/\" rel=\"tag\">th\u1ebf gi\u1edbi t\u1ef1 nhi\u00ean<\/a>, LOCKR n\u1ed5i b\u1eadt so v\u1edbi m\u1ecdi c\u00f4ng c\u1ee5 c\u1ee7a th\u01b0\u01a1ng m\u1ea1i c\u00f4ng ngh\u1ec7 sinh h\u1ecdc, bao g\u1ed3m c\u00e1c c\u00f4ng ngh\u1ec7 g\u1ea7n \u0111\u00e2y nh\u01b0 quang di truy\u1ec1n h\u1ecdc v\u00e0 CRISPR. Trong khi c\u00e1c c\u00f4ng c\u1ee5 ti\u1ec1n th\u00e2n c\u1ee7a n\u00f3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n trong t\u1ef1 nhi\u00ean v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c trang b\u1ecb l\u1ea1i \u0111\u1ec3 s\u1eed d\u1ee5ng trong ph\u00f2ng th\u00ed nghi\u1ec7m, c\u00f4ng nghi\u1ec7p ho\u1eb7c y h\u1ecdc, LOCKR l\u00e0 m\u1ed9t trong nh\u1eefng c\u00f4ng c\u1ee5 c\u00f4ng ngh\u1ec7 sinh h\u1ecdc \u0111\u1ea7u ti\u00ean ho\u00e0n to\u00e0n do con ng\u01b0\u1eddi h\u00ecnh th\u00e0nh v\u00e0 ch\u1ebf t\u1ea1o.<\/p>\n<div class=\"w-100 mb-4 ads\"><\/div>\n<p>C\u00e1c t\u00e1c gi\u1ea3 ch\u00ednh c\u1ee7a b\u00e1o c\u00e1o l\u00e0 Bobby Langan v\u00e0 Scott Boyken thu\u1ed9c Vi\u1ec7n Thi\u1ebft k\u1ebf Protein UW v\u00e0 Andrew Ng c\u1ee7a Ch\u01b0\u01a1ng tr\u00ecnh Sau \u0111\u1ea1i h\u1ecdc UC Berkeley-UCSF v\u1ec1 K\u1ef9 thu\u1eadt Sinh h\u1ecdc.<\/p>\n<p>Langan cho bi\u1ebft: \u201cHi\u1ec7n t\u1ea1i, m\u1ecdi t\u1ebf b\u00e0o \u0111\u1ec1u \u0111ang ph\u1ea3n \u1ee9ng v\u1edbi m\u00f4i tr\u01b0\u1eddng c\u1ee7a n\u00f3. \u201cC\u00e1c t\u1ebf b\u00e0o nh\u1eadn \u0111\u01b0\u1ee3c k\u00edch th\u00edch, sau \u0111\u00f3 ph\u1ea3i t\u00ecm ra nh\u1eefng g\u00ec c\u1ea7n l\u00e0m v\u1edbi n\u00f3. V\u00ed d\u1ee5, h\u1ecd s\u1eed d\u1ee5ng c\u00e1c h\u1ec7 th\u1ed1ng t\u1ef1 nhi\u00ean \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh bi\u1ec3u hi\u1ec7n gen ho\u1eb7c l\u00e0m suy gi\u1ea3m protein.\u201d<\/p>\n<p>Langan v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p c\u1ee7a \u00f4ng b\u1eaft \u0111\u1ea7u t\u1ea1o ra m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 giao ti\u1ebfp v\u1edbi c\u00e1c h\u1ec7 th\u1ed1ng di \u0111\u1ed9ng n\u00e0y. H\u1ecd \u0111\u00e3 s\u1eed d\u1ee5ng t\u00ednh to\u00e1n\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/protein+design\/\" rel=\"tag\">thi\u1ebft k\u1ebf ch\u1ea5t \u0111\u1ea1m<\/a>\u00a0\u0111\u1ec3 t\u1ea1o ra c\u00e1c protein t\u1ef1 l\u1eafp r\u00e1p ch\u1ec9 tr\u00ecnh b\u00e0y c\u00e1c peptide c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc khi b\u1ed5 sung c\u00e1c \u201cch\u00eca kh\u00f3a\u201d ph\u00e2n t\u1eed c\u1ee5 th\u1ec3.<\/p>\n<p>V\u1edbi phi\u00ean b\u1ea3n LOCKR \u0111\u01b0\u1ee3c c\u00e0i \u0111\u1eb7t trong n\u1ea5m men, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 c\u00f3 th\u1ec3 ch\u1ee9ng minh r\u1eb1ng n\u1ea5m bi\u1ebfn \u0111\u1ed5i gen c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u1ea1o ra \u0111\u1ec3 l\u00e0m suy gi\u1ea3m m\u1ed9t lo\u1ea1i protein t\u1ebf b\u00e0o c\u1ee5 th\u1ec3 t\u1ea1i th\u1eddi \u0111i\u1ec3m m\u00e0 c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u l\u1ef1a ch\u1ecdn. B\u1eb1ng c\u00e1ch thi\u1ebft k\u1ebf l\u1ea1i c\u00f4ng t\u1eafc, h\u1ecd c\u0169ng ch\u1ee9ng minh \u0111\u01b0\u1ee3c t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 tr\u00ean t\u1ebf b\u00e0o ng\u01b0\u1eddi \u0111\u01b0\u1ee3c nu\u00f4i c\u1ea5y trong ph\u00f2ng th\u00ed nghi\u1ec7m.<\/p>\n<p>\u0110\u1ec3 gi\u1eef s\u1ee9c kh\u1ecfe, c\u00e1c t\u1ebf b\u00e0o ph\u1ea3i ki\u1ec3m so\u00e1t ch\u1eb7t ch\u1ebd c\u00e1c qu\u00e1 tr\u00ecnh sinh h\u00f3a c\u1ee7a ch\u00fang. Ho\u1ea1t \u0111\u1ed9ng b\u1ea5t th\u01b0\u1eddng ch\u1ec9 \u1edf m\u1ed9t gen ho\u1eb7c s\u1ef1 t\u00edch t\u1ee5 sai lo\u1ea1i protein c\u00f3 th\u1ec3 l\u00e0m \u0111\u1ea3o l\u1ed9n tr\u1ea1ng th\u00e1i c\u00e2n b\u1eb1ng c\u1ee7a t\u1ebf b\u00e0o. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn ch\u1ebft t\u1ebf b\u00e0o ho\u1eb7c th\u1eadm ch\u00ed l\u00e0 ung th\u01b0. LOCKR cung c\u1ea5p cho c\u00e1c nh\u00e0 khoa h\u1ecdc m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c t\u1ebf b\u00e0o s\u1ed1ng. Do \u0111\u00f3, n\u00f3 c\u00f3 th\u1ec3 t\u1ea1o ra m\u1ed9t l\u00e0n s\u00f3ng tr\u1ecb li\u1ec7u m\u1edbi cho c\u00e1c b\u1ec7nh \u0111a d\u1ea1ng nh\u01b0 ung th\u01b0,\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/autoimmune+disorders\/\" rel=\"tag\">R\u1ed1i lo\u1ea1n t\u1ef1 mi\u1ec5n d\u1ecbch<\/a>\u00a0v\u00e0 h\u01a1n th\u1ebf n\u1eefa.<\/p>\n<p>\u201cLOCKR m\u1edf ra m\u1ed9t l\u0129nh v\u1ef1c kh\u1ea3 n\u0103ng ho\u00e0n to\u00e0n m\u1edbi cho vi\u1ec7c l\u1eadp tr\u00ecnh\u00a0<a class=\"textTag\" href=\"https:\/\/phys.org\/tags\/cells\/\" rel=\"tag\">t\u1ebf b\u00e0o<\/a>\u201d, Ng n\u00f3i. \u201cB\u00e2y gi\u1edd ch\u00fang ta b\u1ecb gi\u1edbi h\u1ea1n nhi\u1ec1u h\u01a1n b\u1edfi tr\u00ed t\u01b0\u1edfng t\u01b0\u1ee3ng v\u00e0 kh\u1ea3 n\u0103ng s\u00e1ng t\u1ea1o c\u1ee7a m\u00ecnh h\u01a1n l\u00e0 c\u00e1c protein m\u00e0 thi\u00ean nhi\u00ean \u0111\u00e3 ph\u00e1t tri\u1ec3n.\u201d<\/p>","protected":false},"excerpt":{"rendered":"<p>Scientists have created the first completely artificial protein switch that can work inside living cells to modify\u2014or even commandeer\u2014the cell&#8217;s complex internal circuitry. &nbsp; The switch is dubbed LOCKR, short for Latching, Orthogonal Cage\/Key pRotein. Companion papers published July 24 in the journal\u00a0Nature\u00a0describe LOCKR&#8217;s design and demonstrate several practical applications of the technology. The work<\/p>","protected":false},"author":1,"featured_media":8027,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1,321],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/posts\/8014"}],"collection":[{"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/comments?post=8014"}],"version-history":[{"count":2,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/posts\/8014\/revisions"}],"predecessor-version":[{"id":8758,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/posts\/8014\/revisions\/8758"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/media\/8027"}],"wp:attachment":[{"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/media?parent=8014"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/categories?post=8014"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.huashu-tech.com\/vi\/wp-json\/wp\/v2\/tags?post=8014"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}